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Botox, Xeomin, and Dysport: Understanding the Differences and Achieving a Natural Look

April 21, 2025 by Atagi Plastic Surgery & Skin Aesthetics

Fine Lines, wrinkles

Choosing Between Botox, Xeomin, and Dysport: The Benefits and What to Expect for a Fresh, Natural Look

The fine lines appeared subtly at first—a faint etching on the forehead after long hours at work, a soft crease around the eyes lingering after laughter. The goal wasn’t to reverse time but to preserve a youthful, well-rested look. The search began, not for drastic change, but for a natural, softened appearance. Botox, Dysport, and Xeomin emerged as the three leading neurotoxins reshaping the way people approach aging.

Understanding Neurotoxins: Botox, Dysport, and Xeomin

Each of these injectable treatments temporarily relaxes facial muscles, preventing repeated expressions that deepen lines over time. While they share the same purpose, they have distinct characteristics.

Botox

Botox (onabotulinumtoxinA) is the most well-known neurotoxin. The FDA approved it for cosmetic use in 2002. It contains accessory proteins that may influence how a person responds to treatment over time. Botox provides precise and reliable wrinkle reduction, making it a trusted choice. Results typically appear within 3 to 7 days and last 3 to 4 months (Allergan Aesthetics, 2024).

Dysport

Dysport (abobotulinumtoxinA) has a slightly different formulation, allowing it to spread more easily. This makes it ideal for treating larger areas, such as the forehead. Some patients notice results in as little as 24 to 48 hours. The effects last about 3 to 4 months, similar to Botox (Ipsen Biopharmaceuticals, 2024).

Xeomin

Xeomin (incobotulinumtoxinA) is sometimes called the “naked” neurotoxin because it lacks accessory proteins. This lowers the risk of the body developing resistance. Results appear within 3 to 7 days, and the longevity matches the other two options at 3 to 4 months (Merz Aesthetics, 2024).

Preventative Use: Stopping Wrinkles Before They Start

Neurotoxins are no longer just a solution for existing wrinkles. They have become a strategy for prevention. Using Botox, Dysport, or Xeomin in the late 20s to early 30s slows the formation of deeper lines before they become etched into the skin. Studies show that early intervention can reduce the severity of future wrinkles by up to 30% (American Society of Plastic Surgeons, 2023).

Achieving a Natural Look

Many assume neurotoxins create a frozen, expressionless face. The reality depends on technique and dosing. When applied correctly, these treatments soften movement rather than eliminate it. This preserves natural expressions while reducing harsh lines.

The number of neuromodulator units used directly affects how long your results will last. Higher units generally provide longer-lasting relaxation of targeted muscles. If fewer units are used, results may wear off sooner. Using the appropriate dose ensures optimal longevity and natural-looking results.

At Atagi Aesthetics in Denver, expert injectors customize treatments for each patient’s unique facial anatomy. This ensures results that look refreshed, not overdone. Whether you prefer subtle smoothing or more dramatic wrinkle reduction, we tailor the approach to meet your goals.

Lesser-Known Benefits of Neurotoxins

Botox, Dysport, and Xeomin offer benefits beyond wrinkle prevention:

  • Migraine Relief: Botox can reduce migraine frequency by 50% or more in chronic sufferers (American Migraine Foundation, 2023).
  • Jawline Slimming: Neurotoxins relax the masseter muscles, softening a square jaw and alleviating TMJ symptoms.
  • Sweat Control: Botox is FDA-approved for excessive underarm sweating (hyperhidrosis), providing relief for those with overactive sweat glands.
  • Gummy Smile Correction: Small doses relax the upper lip to prevent excessive gum exposure while smiling.
  • Neck Bands Reduction: Botox smooths vertical neck lines, creating a more youthful appearance.

What to Expect During and After Treatment

The treatment process takes 10 to 20 minutes. A fine needle injects the product into targeted muscles with minimal discomfort, often described as a small pinch.

Minor swelling or redness may appear post-treatment but subsides within a few hours. Results gradually develop over 3 to 7 days, reaching full effect in about two weeks. Regular maintenance treatments sustain a youthful, refreshed appearance.

Choosing the Right Injector

Neurotoxins require both artistry and scientific precision. Choosing the right injector ensures natural and effective results. At Atagi Aesthetics in Denver, we specialize in customized neurotoxin treatments that preserve expressions while preventing deep-set wrinkles.

How to Maximize Results

To extend the longevity of neurotoxin treatments, follow these simple tips:

  • Avoid Rubbing the Treated Area: This prevents the neurotoxin from migrating to unintended areas.
  • Stay Upright for Four Hours: Lying down too soon can affect the distribution of the product.
  • Limit Alcohol and Intense Exercise for 24 Hours: This minimizes the risk of bruising and swelling.
  • Maintain Consistent Treatments: Regular injections train the muscles to contract less forcefully over time, potentially extending the duration of results.

Neurotoxins vs. Other Anti-Aging Treatments

While Botox, Dysport, and Xeomin are excellent for dynamic wrinkles, they do not address volume loss or skin laxity. For comprehensive facial rejuvenation, consider pairing neurotoxin treatments with:

  • Dermal Fillers: Restore lost volume in the cheeks, lips, and nasolabial folds.
  • Broadband Light (BBL) Therapy: Targets sun damage, redness, and brown spots for an even skin tone.
  • Microneedling with Radiofrequency: Stimulates collagen production to improve skin texture and firmness.
  • Laser Resurfacing, such as MicroLaser Peel and Profractional: Reduces fine lines, wrinkles, and pigmentation concerns.

Debunking Common Myths About Neurotoxins

  • Myth: Botox, Dysport, and Xeomin are toxic.
    • Truth: These treatments use purified proteins in controlled doses, making them safe and effective.
  • Myth: Stopping neurotoxin treatments makes wrinkles worse.
    • Truth: Wrinkles return gradually to their natural state if treatments stop, but they do not worsen.
  • Myth: Neurotoxins only work for older individuals.

    • Truth: Preventative treatments in younger patients help delay the onset of deep lines.

Slow the Aging Process with Expert Care

Aging gracefully doesn’t mean erasing every line. It means enhancing natural beauty in a way that feels authentic. How could Botox, Dysport, or Xeomin fit into your long-term skincare plan?

 

Filed Under: Botox & Dermal Fillers Category, BOTOX Category, Xeomin Category Tagged With: Anti- aging treatment, Botox, Dysport, Fine Lines, Natural Look, Neurotoxin, Softened appearance, Wrinkles, Xeomin

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